SCHEMBL9489154

SCHEMBL9489154

COc1c(N)c(N)c(OC)c(OC)c1OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP19A1 P11511 2/20 0.33
NQO2 P16083 1/20 0.33
TUBB4A P04350 3/20 0.32
TUBB P07437 3/20 0.32
TUBA3C P0DPH7 3/20 0.32
TUBA1B P68363 3/20 0.32
TUBA4A P68366 3/20 0.32
TUBB4B P68371 3/20 0.32
TUBB3 Q13509 3/20 0.32
TUBB2A Q13885 3/20 0.32
TUBB8 Q3ZCM7 3/20 0.32
TUBA3E Q6PEY2 3/20 0.32
TUBA1A Q71U36 3/20 0.32
TUBA1C Q9BQE3 3/20 0.32
TUBB6 Q9BUF5 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20821452 0.92 KDM4E (0.37) KDM4EPOLBALDH1A1MAPK1SMN1; SMN2
SCHEMBL7627662 0.79 ACHE (0.33) KDM4EPOLBALDH1A1MAPK1SMN1; SMN2
SCHEMBL8213378 0.78 ALDH1A1 (0.44) KDM4EPOLBALDH1A1MAPK1SMN1; SMN2
SCHEMBL11844285 0.76 CA2 (0.46) KDM4EPOLB
SCHEMBL18949191 0.72
SCHEMBL11476309 0.71 ALDH1A1 (0.61) KDM4EPOLBALDH1A1MAPK1SMN1; SMN2
SCHEMBL6384362 0.69 ACHE (0.32) ACHE
SCHEMBL22927084 0.69 ACHE (0.32) ACHE
SCHEMBL15212338 0.68
SCHEMBL9348395 0.68 KDM4E (0.55) KDM4EPOLBCYP19A1NQO2TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714954-A1 FUSED POLYCYCLIC COMPOUNDS AS ELECTRODE ACTIVE MATERIALS FOR AQUEOUS AND NON-AQUEOUS SECONDARY BATTERIES Kemijski Institut (SI) 2026-03-25 EP disclosed
US-5233089-A Charge transport material; used in electrophotographic plates to provide improved sensitivity, photoresponse and durability HITACHI, LTD. (JP) 1993-08-03 US disclosed
EP-0273426-B1 ENAMINE DERIVATIVES, PRODUCTION THEREOF AND ELECTROPHOTOGRAPHIC PLATES CONTAINING THE SAME Hitachi Chemical Co., Ltd. (JP) 1993-03-17 EP disclosed
EP-0273426-A2 Enamine derivatives, production thereof and electrophotographic plates containing the same Hitachi Chemical Co., Ltd. (JP) 1988-07-06 EP disclosed