Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490130 | 0.92 | NPC1 (0.40) | NPC1RAB9ATAS1R3TAS1R1HPGD | |
| SCHEMBL9490953 | 0.82 | ALDH1A1 (0.39) | TAS1R3TAS1R1HPGDALDH1A1KDM4E | |
| SCHEMBL9489780 | 0.78 | HPGD (0.46) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL23640269 | 0.62 | AOC3 (0.42) | NPC1RAB9AHPGDALDH1A1AOC3 | |
| SCHEMBL10652594 | 0.61 | CLCN2 (0.39) | HPGDALDH1A1KDM4ECNR2SLC6A2 | |
| SCHEMBL9352835 | 0.61 | ALDH1A1 (0.41) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL8980406 | 0.61 | NPC1 (0.48) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL9353018 | 0.60 | AOC3 (0.38) | NPC1RAB9ATAS1R3TAS1R1CNR2 | |
| SCHEMBL9489186 | 0.60 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1AOC3KMT2A | |
| SCHEMBL22183793 | 0.60 | HDAC3 (0.43) | RAB9AHPGDALDH1A1AOC3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180419-A | Herbicidal 2-(2-imidazolin-2-yl)-benzo-(5-membered)-heterocycles and the use thereof | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |