SCHEMBL9490953

SCHEMBL9490953

CC(C)C(C)(NC(=O)c1ccc2c(c1C(=O)O)OCO2)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 2/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
CNR2 P34972 1/20 0.37
POLB P06746 3/20 0.36
AOC3 Q16853 1/20 0.34
MAPT P10636 3/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
PKM P14618 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SRD5A2 P31213 1/20 0.32
MAPK1 P28482 1/20 0.31
KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9490130 0.86 NPC1 (0.40) ALDH1A1KDM4ETAS1R3TAS1R1CNR2
SCHEMBL9489248 0.82 NPC1 (0.40) ALDH1A1KDM4ETAS1R3TAS1R1CNR2
SCHEMBL10652599 0.75 CNR2 (0.36) ALDH1A1KDM4ECNR2MEN1KMT2A
SCHEMBL9489186 0.73 ALDH1A1 (0.46) ALDH1A1POLBAOC3PKMMEN1
SCHEMBL10674576 0.72 ALDH1A1 (0.44) ALDH1A1KDM4EPOLBMAPTCYP1A2
SCHEMBL10679364 0.70 CSNK2A1 (0.41) ALDH1A1KDM4ECNR2GAAMEN1
SCHEMBL10674816 0.70 SORT1 (0.43) ALDH1A1KDM4ECNR2MEN1KMT2A
SCHEMBL10674834 0.70 GRM1 (0.44) ALDH1A1KDM4ECNR2CYP1A2MEN1
SCHEMBL10652594 0.68 CLCN2 (0.39) ALDH1A1KDM4ECNR2GAAHPGD
SCHEMBL9855899 0.66 HPGD (0.45) ALDH1A1KDM4EPOLBMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5180419-A Herbicidal 2-(2-imidazolin-2-yl)-benzo-(5-membered)-heterocycles and the use thereof AMERICAN CYANAMID COMPANY (US) 1993-01-19 US disclosed