Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | RRM1 | P23921 | 1/20 | 0.53 |
| ▸ | RRM2 | P31350 | 1/20 | 0.53 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.53 |
| ▸ | S100B | P04271 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405416 | 0.95 | CA2 (0.61) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL10405415 | 0.95 | CA2 (0.61) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL8094327 | 0.91 | CA1 (0.76) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL14164182 | 0.91 | CA1 (0.76) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL11585493 | 0.86 | PTGS2 (0.69) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL11585488 | 0.86 | PTGS2 (0.69) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL11585495 | 0.86 | PTGS2 (0.69) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL9458165 | 0.83 | PTGS2 (0.66) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL9357922 | 0.83 | PTGS2 (0.66) | CA2PTGS2CA1CA12CA9 | |
| SCHEMBL12972525 | 0.83 | PTGS2 (0.70) | CA2PTGS2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250099-B1 | ORGANIC NONLINEAR OPTICAL MATERIAL | TORAY INDUSTRIES, INC. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5169986-A | Benzylidene-aniline derivative; laser resistance, durability | TORAY INDUSTRIES, INC. (JP) | 1992-12-08 | — | — | US | disclosed |
| US-4987255-A | EXCELLENT RESISTANCE TO LASER DAMAGE | TORAY INDUSTRIES, INC. (JP) | 1991-01-22 | — | — | US | disclosed |