Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445182 | 0.82 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL28394865 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2POLBMAPTKDM4E | |
| SCHEMBL9241814 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2POLBMAPTKDM4E | |
| SCHEMBL16181674 | 0.80 | CA1 (0.35) | GABRA1GABRB2TSHRMAPTKDM4E | |
| SCHEMBL561428 | 0.78 | CYP3A4 (0.46) | POLBTSHRMAPTRXRARXRB | |
| SCHEMBL28990026 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2POLBRXRARXRB | |
| SCHEMBL72636 | 0.75 | TSHR (0.52) | POLBTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL93161 | 0.74 | GABRA1 (0.69) | GABRA1GABRB2POLBTSHRMAPT | |
| SCHEMBL3807248 | 0.74 | ALDH1A1 (0.53) | GABRA1GABRB2POLBMAPTKDM4E | |
| SCHEMBL11677895 | 0.73 | TSHR (0.50) | POLBTSHRMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114690559-A | Photosensitive resin composition, cured film and display device | 株式会社东进世美肯 | 2022-07-01 | — | — | CN | disclosed |
| US-11352324-B2 | Methods | MEDIMMUNE LIMITED (GB) | 2022-06-07 | — | — | US | disclosed |
| US-20200399215-A1 | METHODS | MEDIMMUNE LIMITED (GB) | 2020-12-24 | — | — | US | disclosed |
| US-7875686-B2 | comprising 10 to 99 wt. % of norbornene-type cycloolefin monomers; for microelectronic, optoelectronic and micro-optoelectronic applications such as die attach adhesives, underfill materials, prepreg binders, encapsulants | PROMERUS LLC (US) | 2011-01-25 | — | — | US | disclosed |
| US-7534539-B2 | Electrophotographic photoreceptor and image forming apparatus having the same | SHARP KABUSHIKI KAISHA (JP) | 2009-05-19 | — | — | US | disclosed |
| EP-1791888-B1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1791888-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | Promerus, LLC (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006023511-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060041093-A1 | Polycycloolefin polymeric compositions for semiconductor applications | SUMITOMO BAKELITE CO., LTD. (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-0517843-A1 | POLYUREA GEL COMPOSITIONS AND ARTICLES THEREFROM | RAYCHEM CORPORATION (US) | 1992-12-16 | — | — | EP | disclosed |
| US-5104930-A | Sealing and protecting substrates; tensile strength, elongation, toughness, compatibility | RAYCHEM CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |
| WO-1991013109-A1 | POLYUREA GEL COMPOSITIONS AND ARTICLES THEREFROM | RAYCHEM CORPORATION (US) | 1991-09-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352324-B2 | Methods | SIN3A, RCC2, RPS3 | GABRA1 3687/4885GABRB2 2834/4885POLB 1821/4885 |
| US-20200399215-A1 | METHODS | SIN3A, RCC2, RPS3 | GABRA1 3687/4885GABRB2 2834/4885POLB 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.