Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GPR88 | Q9GZN0 | 11/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489480 | 1.00 | FFAR1 (0.57) | FFAR1MAPTGPR88GAAMEN1 | |
| SCHEMBL9488760 | 0.91 | GPR88 (0.53) | GPR88 | |
| SCHEMBL9488765 | 0.91 | GPR88 (0.53) | GPR88 | |
| SCHEMBL9487480 | 0.89 | MAPT (0.49) | FFAR1MAPTGPR88GAAMEN1 | |
| SCHEMBL9487487 | 0.89 | MAPT (0.49) | FFAR1MAPTGPR88GAAMEN1 | |
| SCHEMBL9488693 | 0.89 | GAA (0.50) | MAPTGAAKMT2AADRB2ADRB1 | |
| SCHEMBL9488748 | 0.87 | KMT2A (0.50) | MAPTGAAMEN1KMT2A | |
| SCHEMBL9488768 | 0.85 | TSHR (0.51) | MAPTMEN1KMT2AADRB2ADRB1 | |
| SCHEMBL9490540 | 0.85 | ADRB2 (0.54) | MAPTGPR88KMT2AADRB2ADRB1 | |
| SCHEMBL9487982 | 0.84 | MAPT (0.52) | FFAR1MAPTADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | claimed |
| US-5236618-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0168043-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1990-11-07 | — | — | EP | disclosed |
| US-4744918-A | Liquid crystal phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-05-17 | — | — | US | disclosed |