Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13556994 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL11390540 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8371512 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL7079626 | 0.86 | TDP1 (0.59) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL21104599 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL21104611 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3068736 | 0.81 | TDP1 (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL11383524 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL19018472 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL13874349 | 0.80 | DRD2 (0.47) | MAPTSMN1; SMN2HPGDLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368717-B1 | 5-BENZYLIDENE 3-OXA CYCLOPENTANONE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN COSMETIC COMPOSITIONS TO PROTECT THE SKIN AND THE HAIR AGAINST SUN RADIATION | L'OREAL (FR) | 1993-01-20 | — | — | EP | disclosed |
| EP-0368717-A1 | 5-Benzylidene 3-oxa cyclopentanone derivatives, process for their manufacture and their use in cosmetic compositions to protect the skin and the hair against sun radiation | L'OREAL (FR) | 1990-05-16 | — | — | EP | disclosed |