Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068736 | 0.95 | TDP1 (0.54) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL19018472 | 0.91 | ALDH1A1 (0.60) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8371512 | 0.89 | ALDH1A1 (0.57) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL31498248 | 0.88 | ALDH1A1 (0.57) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11806698 | 0.87 | ALDH1A1 (0.53) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL28512770 | 0.87 | ALDH1A1 (0.53) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7283005 | 0.86 | RARB (0.56) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL21104599 | 0.86 | ALDH1A1 (0.54) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL21104611 | 0.86 | ALDH1A1 (0.54) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9489504 | 0.86 | ALDH1A1 (0.54) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| WO-2022214995-A1 | PROBE DIRECTED TO ENZYME ALDH1A3 AND USE THEREOF IN THE DIAGNOSIS OF GLIOBLASTOMA | UNIVERSITA' DEGLI STUDI DEL PIEMONTE ORIENTALE "A. AVOGADRO" (IT) | 2022-10-13 | — | — | WO | disclosed |
| US-10655029-B2 | Inkjet ink and coloring composition | RICOH COMPANY, LTD. (JP) | 2020-05-19 | — | — | US | disclosed |
| US-20180094155-A1 | INKJET INK AND COLORING COMPOSITION | RICOH COMPANY, LTD. (JP) | 2018-04-05 | — | — | US | disclosed |
| US-20180094155-A1 | INKJET INK AND COLORING COMPOSITION | RICOH COMPANY, LTD. (JP) | 2018-04-05 | — | — | US | disclosed |
| CN-105503652-B | Cyano-containing resveratrol analogses and its production and use | 延边大学 | 2017-12-05 | — | — | CN | disclosed |
| US-9592221-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-03-14 | — | — | US | disclosed |
| US-9592221-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-15 | — | — | US | disclosed |
| EP-1324971-A2 | CINNAMIC ACID ESTER | HAARMANN & REIMER GMBH (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6531625-B2 | Condensation of benzaldehyde with ester | HAARMANN & REIMBER GMBH (DE) | 2003-03-11 | — | — | US | disclosed |
| US-20020133038-A1 | Cinnamic esters | SYMRISE GMBH & CO. KG (DE) | 2002-09-19 | — | — | US | disclosed |
| WO-2002020456-A2 | PRODUCTION OF CINNAMIC ACID ESTERS | HAARMANN & REIMER GMBH (DE) | 2002-03-14 | — | — | WO | disclosed |
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | POLRMT, POLR1C, FBL | TDP1 1637/4885ALDH1A1 1785/4885MAPT 4817/4885 |
| US-20020133038-A1 | Cinnamic esters | ACACB, CES2, FASN | TDP1 4707/4885ALDH1A1 158/4885MAPT 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.