Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789027 | 0.83 | PKM (0.59) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL5250030 | 0.82 | MEN1 (1.00) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL30926569 | 0.82 | MEN1 (1.00) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL13985217 | 0.81 | TDP1 (0.75) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL8789825 | 0.79 | PKM (0.56) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL4897703 | 0.76 | ALDH1A1 (0.66) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL9489390 | 0.76 | HSD17B10 (0.77) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL13985123 | 0.76 | HSD17B10 (0.80) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL9491573 | 0.76 | ALDH1A1 (1.00) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL29562691 | 0.74 | ALDH1A1 (0.63) | MEN1KMT2APOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266102-B1 | QUINOXALINONE DERIVATIVES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0266102-A2 | Quinoxalinone derivatives | PFIZER INC. (US) | 1988-05-04 | — | — | EP | disclosed |