Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489390 | 0.83 | HSD17B10 (0.77) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL29562691 | 0.81 | ALDH1A1 (0.63) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL9491573 | 0.80 | ALDH1A1 (1.00) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL9489643 | 0.76 | MEN1 (0.73) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL9491786 | 0.75 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL30926569 | 0.75 | MEN1 (1.00) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL5250030 | 0.75 | MEN1 (1.00) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL9489593 | 0.75 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL30926480 | 0.75 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTHSD17B10MEN1 | |
| SCHEMBL27180096 | 0.75 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351709-B2 | Estrogen receptor ligands | WYETH (US) | 2008-04-01 | — | — | US | disclosed |
| US-20060019961-A1 | Estrogen receptor ligands | WYETH | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019961-A1 | Estrogen receptor ligands | GPER1, ESR2, ESR1 | ALDH1A1 1051/4885POLB 4581/4885MAPT 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.