Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906702 | 0.89 | RAPGEF4 (0.40) | RAPGEF4TAAR1NR3C1NR3C2PGR | |
| SCHEMBL18919877 | 0.87 | TAAR1 (0.46) | RAPGEF4TAAR1NR3C1NR3C2POLB | |
| SCHEMBL8905155 | 0.86 | TAAR1 (0.47) | RAPGEF4TAAR1NR3C1NR3C2POLB | |
| SCHEMBL27625494 | 0.79 | POLB (0.42) | RAPGEF4TAAR1NR3C1NR3C2PGR | |
| SCHEMBL4279450 | 0.77 | TRPA1 (0.44) | RAPGEF4TAAR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL269825 | 0.75 | TAAR1 (0.58) | TAAR1NR3C1NR3C2POLBTP53 | |
| SCHEMBL168406 | 0.75 | PYCR1 (0.46) | RAPGEF4TAAR1NR3C1NR3C2PGR | |
| SCHEMBL29462885 | 0.75 | TAAR1 (0.58) | TAAR1NR3C1NR3C2POLBTP53 | |
| SCHEMBL5498171 | 0.73 | TRPA1 (0.44) | RAPGEF4TAAR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL169507 | 0.73 | TRPA1 (0.44) | RAPGEF4TAAR1TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177286-A | Selective production of a p-alkyltoluene or 4,4'-alkylmethylbiphenyl | AMOCO CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |