Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489658 | 0.74 | RXFP1 (0.51) | PLK1MAPTKDM4ELMNANPSR1 | |
| SCHEMBL11564885 | 0.65 | GPR35 (0.47) | PLK1GPR35MAPTTSHRCYP3A4 | |
| SCHEMBL14272018 | 0.65 | CREBBP (0.75) | GPR35MAPTTSHRCYP3A4KDM4E | |
| SCHEMBL9489085 | 0.63 | GRIN2D (0.54) | GPR35MAPTTSHRCYP3A4KDM4E | |
| SCHEMBL322531 | 0.62 | GPR35 (1.00) | GPR35MAPTTSHRCYP3A4KDM4E | |
| SCHEMBL11539985 | 0.62 | GPR35 (0.68) | GPR35MAPTTSHRCYP3A4KDM4E | |
| SCHEMBL1286322 | 0.61 | GPR35 (0.61) | GPR35MAPTTSHRCYP3A4KDM4E | |
| SCHEMBL260768 | 0.61 | GPR35 (0.67) | GPR35MAPTTSHRCYP3A4KDM4E | |
| SCHEMBL28836799 | 0.61 | GPR35 (0.55) | GPR35MAPTTSHRCYP3A4KDM4E | |
| SCHEMBL19785779 | 0.61 | GPR35 (0.55) | GPR35MAPTTSHRCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096910-A | For plants | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | claimed |
| US-5096910-A | For plants | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| EP-0391188-A1 | Fungicide agents based on partly known nitro substituted benzothiazolones, new nitro substituted benzothiazolones and process for their preparation | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |