Methylene Chloride

Methylene Chloride

SCHEMBL9490200

CC(C)=CCOC(=N)C(Cl)(Cl)Cl.ClCCl

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232511 0.96 ALDH1A1 (0.33) ALDH1A1ALOX15
SCHEMBL1685646 0.71 ALOX15 (0.41) ALDH1A1ALOX15
SCHEMBL8715654 0.71
SCHEMBL1288241 0.70 CYP3A4 (0.32)
SCHEMBL8719152 0.69
SCHEMBL8719153 0.69
SCHEMBL8718871 0.68
Cyclohexane SCHEMBL9488552 0.67
SCHEMBL17106541 0.66
Cyclohexane SCHEMBL8719141 0.65 ALDH1A1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5208228-A Skin disorders MERCK & CO., INC. (US) 1993-05-04 US disclosed
US-5162334-A Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity MERCK & CO., INC. (US) 1992-11-10 US disclosed