Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803249 | 0.96 | SIRT5 (0.54) | SIRT5HDAC1SIRT2SIRT1SIRT3 | |
| SCHEMBL8495706 | 0.93 | CTSL (0.54) | SIRT5HDAC1SIRT2SIRT1 | |
| SCHEMBL8495526 | 0.93 | CTSL (0.54) | SIRT5HDAC1SIRT2SIRT1 | |
| SCHEMBL29790888 | 0.86 | CPB1 (0.61) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL8342384 | 0.86 | HDAC1 (0.49) | SIRT5HDAC1SIRT2SIRT1SIRT3 | |
| Hydrochloric Acid SCHEMBL9814916 | 0.85 | HDAC1 (0.48) | SIRT5HDAC1SIRT2SIRT1SIRT3 | |
| SCHEMBL8338954 | 0.84 | NPY4R (0.46) | — | |
| SCHEMBL3868955 | 0.84 | SIRT5 (0.52) | SIRT5MMP3 | |
| SCHEMBL3868962 | 0.84 | SIRT5 (0.52) | SIRT5MMP3 | |
| SCHEMBL9490193 | 0.83 | SIRT2 (0.48) | SIRT5HDAC1SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255341-B1 | REAGENT FOR TESTING PERIODONTAL DISEASES | SUNSTAR KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5137811-A | Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria | SUNSTAR KABUSHIKI KAISHA (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0255341-A2 | Reagent for testing periodontal diseases | SUNSTAR KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | disclosed |