Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.65 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490611 | 0.99 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL9491966 | 0.96 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL9491275 | 0.94 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL2796287 | 0.86 | POLB (0.71) | MTNR1AMTNR1BALDH1A1KDM4EPOLB | |
| SCHEMBL8097845 | 0.84 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL7417587 | 0.82 | ALDH1A1 (0.70) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL9131926 | 0.81 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2ALDH1A1HSD17B10 | |
| SCHEMBL31176222 | 0.81 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2ALDH1A1HSD17B10 | |
| SCHEMBL8961302 | 0.81 | MTNR1A (0.90) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL11735352 | 0.81 | ALDH1A1 (0.72) | ALDH1A1KDM4EMEN1KMT2APTBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225442-A | Melatoninergic disorders | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | disclosed |