Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23772363 | 0.89 | TRPV1 (0.55) | TRPV1EPHX2ATMNPY5RSLC6A9 | |
| SCHEMBL9854680 | 0.89 | TRPV1 (0.55) | TRPV1EPHX2ATMNPY5RSLC6A9 | |
| SCHEMBL9854669 | 0.87 | TRPV1 (0.53) | TRPV1EPHX2ATMNPY5RSLC6A9 | |
| SCHEMBL14957415 | 0.86 | TRPV1 (0.52) | TRPV1SLC6A9 | |
| SCHEMBL3094360 | 0.84 | SLC6A9 (0.50) | TRPV1NPY5RSLC6A9 | |
| SCHEMBL3111835 | 0.82 | DRD2 (0.47) | TRPV1SLC6A9 | |
| SCHEMBL4297282 | 0.80 | MEN1 (0.58) | TRPV1NPY5R | |
| Bromide SCHEMBL1593622 | 0.79 | MEN1 (0.57) | TRPV1NPY5R | |
| SCHEMBL30685627 | 0.78 | HTT (0.46) | EPHX2 | |
| SCHEMBL30685636 | 0.78 | ATM (0.47) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272157-A | Derivatives of 4-(aminomethyl) piperidine, their preparation and their therapeutic application | SYNTHELABO (FR) | 1993-12-21 | — | — | US | disclosed |
| US-5179108-A | Antiserotonin agents or cardiovascular disorders | SYNTHELABO (FR) | 1993-01-12 | — | — | US | disclosed |