Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23772363 | 1.00 | TRPV1 (0.55) | TRPV1MTNR1AMTNR1BEPHX2SLC6A9 | |
| SCHEMBL9490339 | 0.89 | TRPV1 (0.57) | TRPV1EPHX2SLC6A9ATMNPY5R | |
| SCHEMBL9854669 | 0.87 | TRPV1 (0.53) | TRPV1MTNR1AMTNR1BEPHX2SLC6A9 | |
| SCHEMBL4297282 | 0.81 | MEN1 (0.58) | TRPV1NPY5R | |
| Bromide SCHEMBL1593622 | 0.80 | MEN1 (0.57) | TRPV1NPY5R | |
| SCHEMBL3101298 | 0.79 | SLC6A9 (0.50) | TRPV1SLC6A9NPY5R | |
| SCHEMBL11138133 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL23772365 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL7270673 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL7273542 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420064-A2 | Substituted 2-amidotetralins as melatonin agonists and antagonists | NORTHWESTERN UNIVERSITY (US) | 1991-04-03 | — | — | EP | disclosed |