Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490929 | 0.95 | KMT2A (0.43) | KMT2AALDH1A1MAPTUSP2MEN1 | |
| SCHEMBL9489892 | 0.89 | KMT2A (0.45) | KMT2AALDH1A1MAPTUSP2MEN1 | |
| SCHEMBL9490939 | 0.86 | KMT2A (0.40) | KMT2A | |
| SCHEMBL9488909 | 0.85 | KMT2A (0.45) | KMT2AALDH1A1MAPTUSP2MEN1 | |
| SCHEMBL9488618 | 0.84 | POLB (0.41) | KMT2AMAPTMEN1HSD17B10POLB | |
| SCHEMBL9490428 | 0.82 | NPC1 (0.45) | KMT2AMAPTMEN1HSD17B10POLB | |
| SCHEMBL9374070 | 0.82 | THRA (0.40) | KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL9372611 | 0.81 | MEN1 (0.40) | KMT2AALDH1A1MEN1 | |
| SCHEMBL9373091 | 0.80 | MEN1 (0.38) | KMT2AALDH1A1MEN1KDM4EGAA | |
| SCHEMBL9371859 | 0.80 | MTNR1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |