SCHEMBL949042

SCHEMBL949042

c1ccc(CC(NC2=NCCN2)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ NPSR1 Q6W5P4 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ CYP1A2 P05177 2/20 0.51
▸ CYP2D6 P10635 2/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ NISCH Q9Y2I1 8/20 0.49
▸ MAOA P21397 7/20 0.49
▸ MAOB P27338 7/20 0.49
▸ ADRA2A P08913 5/20 0.44
▸ ADRA2B P18089 5/20 0.44
▸ ADRA2C P18825 5/20 0.44
▸ TAAR1 Q96RJ0 2/20 0.44
▸ ADRA1D P25100 2/20 0.44
▸ ADRA1A P35348 2/20 0.44
▸ ADRA1B P35368 2/20 0.44
▸ LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL951481 0.99 KDM4E (0.51) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4788335 0.93 CYP1A2 (0.48) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4788615 0.91 PTGIR (0.44) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4788401 0.91 KDM4E (0.44) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4788602 0.91 NISCH (0.44) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4785397 0.91 PTGIR (0.47) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL12637713 0.90 CYP1A2 (0.58) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4787326 0.90 CYP1A2 (0.58) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4114349 0.87 WDR5 (0.48) KDM4EHTTNPSR1L3MBTL1CYP1A2
SCHEMBL4786568 0.87 HTR1B (0.49) KDM4EHTTNPSR1L3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871960-B2 1-(Imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2011-01-18 — — US claimed
EP-1888533-B1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2010-12-15 — — EP claimed
US-20080200335-A1 1-(Imidazolin-2-Yl)Amino-1,2-Diphenylethane Compounds For Combating Animal Pests BASF AKTIENGESELLSCHAFT (DE) 2008-08-21 — — US claimed
EP-1888533-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2008-02-20 — — EP claimed
WO-2006125748-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO claimed
WO-2021080160-A1 MOSQUITO-PREVENTING COMPOSITION USING MYRISTICA FRAGANS EXTRACT, AND PREVENTION METHOD USING SAME 재단법인 경기도경제과학진흥원 2021-04-29 — — WO disclosed
CN-101184737-B 1-(imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE 2012-12-26 — — CN disclosed
CN-101184737-B 1-(imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE 2012-12-26 — — CN disclosed
US-8221775-B2 Pyrrolin-2-ylamino compounds for combating animal pests BASF SE (DE) 2012-07-17 — — US disclosed
EP-2346822-A1 PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2011-07-27 — — EP disclosed
US-20110160269-A1 Pyrrolin-2-ylamino Compounds For Combating Animal Pests BASF SE 2011-06-30 — — US disclosed
US-7871960-B2 1-(Imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2011-01-18 — — US disclosed
CN-101184737-A 1-(imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2008-05-21 — — CN disclosed
CN-101184737-A 1-(imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2008-05-21 — — CN disclosed
EP-1888533-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2008-02-20 — — EP disclosed
EP-1888533-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2008-02-20 — — EP disclosed
EP-1888533-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2008-02-20 — — EP disclosed
WO-2006125748-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006125748-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006125748-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200335-A1 1-(Imidazolin-2-Yl)Amino-1,2-Diphenylethane Compounds For Combating Animal Pests ANXA1, ANXA11, AGO2 KDM4E 2092/4885HTT 3597/4885NPSR1 2421/4885
US-20110160269-A1 Pyrrolin-2-ylamino Compounds For Combating Animal Pests RXFP3, CBR3, ATL3 KDM4E 2070/4885HTT 2503/4885NPSR1 285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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