Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CPT1A | P50416 | 4/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 3/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490262 | 0.89 | ITGA4 (0.36) | KDM4EGAAALDH1A1ITGA4ITGB7 | |
| SCHEMBL9490652 | 0.87 | MEN1 (0.40) | ALDH1A1ITGA4ITGB7P2RX7 | |
| SCHEMBL9491683 | 0.87 | P2RX7 (0.35) | KDM4EGAAALDH1A1ITGA4ITGB7 | |
| SCHEMBL10432053 | 0.87 | MEN1 (0.40) | ALDH1A1ITGA4ITGB7P2RX7 | |
| SCHEMBL10431870 | 0.87 | P2RX7 (0.35) | KDM4EGAAALDH1A1ITGA4ITGB7 | |
| SCHEMBL9491888 | 0.87 | ITGA4 (0.37) | GAAALDH1A1ITGA4ITGB7P2RX7 | |
| SCHEMBL9491885 | 0.86 | CYP1A2 (0.39) | KDM4EMAPTALDH1A1ITGA4ITGB7 | |
| SCHEMBL9521814 | 0.86 | CYP1A2 (0.39) | KDM4EMAPTALDH1A1ITGA4ITGB7 | |
| SCHEMBL9520740 | 0.85 | ITGA4 (0.36) | GAAALDH1A1ITGA4ITGB7P2RX7 | |
| SCHEMBL9491001 | 0.85 | GAA (0.37) | GAAALDH1A1ITGA4ITGB7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246950-A | Smooth muscle disorders | RHONE-POULENC SANTE (FR) | 1993-09-21 | — | — | US | disclosed |
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |
| EP-0390693-A1 | Thioformamide derivatives | RHONE-POULENC SANTE (FR) | 1990-10-03 | — | — | EP | disclosed |