Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733234 | 0.76 | CA4 (0.42) | ATML3MBTL1CA4MTNR1AMTNR1B | |
| SCHEMBL8718949 | 0.74 | ATM (0.40) | ATML3MBTL1CA4MTNR1AMTNR1B | |
| SCHEMBL7417657 | 0.74 | MTNR1A (0.43) | CA4MTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL14463423 | 0.74 | ATM (0.40) | ATML3MBTL1CA4MTNR1AMTNR1B | |
| SCHEMBL11911977 | 0.74 | ATM (0.40) | ATML3MBTL1CA4MTNR1AMTNR1B | |
| SCHEMBL7322928 | 0.74 | ATM (0.49) | ATML3MBTL1MTNR1AMTNR1BGAA | |
| SCHEMBL57754 | 0.73 | MTNR1A (0.46) | CA4MTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL295469 | 0.73 | ATM (0.43) | ATML3MBTL1CA4MTNR1AMTNR1B | |
| SCHEMBL7322935 | 0.72 | L3MBTL1 (0.40) | ATML3MBTL1CA4MTNR1AMTNR1B | |
| SCHEMBL312762 | 0.72 | ATM (0.40) | ATML3MBTL1CA4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077646-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | WO | disclosed |