Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.53 |
| ▸ | DPP4 | P27487 | 3/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25122378 | 0.86 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4CYP2D6HTT | |
| SCHEMBL23007438 | 0.86 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4CYP2D6HTT | |
| SCHEMBL25122224 | 0.86 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4CYP2D6HTT | |
| SCHEMBL25122278 | 0.86 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4CYP2D6HTT | |
| SCHEMBL25122248 | 0.86 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4CYP2D6HTT | |
| SCHEMBL25122261 | 0.86 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4CYP2D6HTT | |
| SCHEMBL8116561 | 0.84 | DPP4 (0.53) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL9489209 | 0.84 | ALDH1A1 (0.48) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL9489213 | 0.84 | ALDH1A1 (0.48) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL9490129 | 0.81 | DPP8 (0.64) | DPP8DPP7DPP4ACENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255341-B1 | REAGENT FOR TESTING PERIODONTAL DISEASES | SUNSTAR KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5137811-A | Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria | SUNSTAR KABUSHIKI KAISHA (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0255341-A2 | Reagent for testing periodontal diseases | SUNSTAR KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | disclosed |