Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.64 |
| ▸ | DPP4 | P27487 | 3/20 | 0.64 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PRSS8 | Q16651 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488227 | 0.92 | DPP8 (0.57) | DPP8DPP4DPP7STAT6ACE | |
| SCHEMBL4955191 | 0.85 | DPP8 (0.71) | DPP8DPP4DPP7ACEPRSS8 | |
| SCHEMBL9040814 | 0.85 | DPP8 (0.71) | DPP8DPP4DPP7ACEPRSS8 | |
| SCHEMBL7326774 | 0.84 | DPP8 (0.70) | DPP8DPP4DPP7ACEALDH1A1 | |
| SCHEMBL9040522 | 0.82 | DPP4 (0.67) | DPP8DPP4DPP7ACELMNA | |
| SCHEMBL9040510 | 0.82 | DPP4 (0.67) | DPP8DPP4DPP7ACELMNA | |
| SCHEMBL9490722 | 0.81 | DPP8 (0.54) | DPP8DPP4DPP7ACEALDH1A1 | |
| SCHEMBL7264291 | 0.81 | DPP8 (0.66) | DPP8DPP4DPP7ACEALDH1A1 | |
| Methanesulfonamide SCHEMBL11099377 | 0.80 | DPP8 (0.65) | DPP8DPP4DPP7ACEPRSS8 | |
| Hydrochloric Acid SCHEMBL7264261 | 0.80 | DPP8 (0.65) | DPP8DPP4DPP7ACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255341-B1 | REAGENT FOR TESTING PERIODONTAL DISEASES | SUNSTAR KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5137811-A | Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria | SUNSTAR KABUSHIKI KAISHA (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0255341-A2 | Reagent for testing periodontal diseases | SUNSTAR KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | disclosed |