Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489128 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TSHRHSD17B10RECQLKMT2A | |
| SCHEMBL27678042 | 0.78 | MEN1 (0.39) | HSD17B10KMT2AMEN1MAPTPAX8 | |
| SCHEMBL10764482 | 0.75 | RECQL (0.47) | ALDH1A1TSHRHSD17B10RECQLKMT2A | |
| SCHEMBL7751907 | 0.62 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10RECQLKMT2A | |
| SCHEMBL399612 | 0.62 | KMT2A (0.43) | ALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL9490741 | 0.60 | RECQL (0.53) | ALDH1A1TSHRHSD17B10RECQLKMT2A | |
| SCHEMBL10560087 | 0.60 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10RECQLKMT2A | |
| SCHEMBL28784476 | 0.59 | TSHR (0.42) | ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9299891 | 0.59 | RECQL (0.52) | ALDH1A1TSHRHSD17B10RECQLKMT2A | |
| SCHEMBL11799382 | 0.59 | PDK2 (0.38) | ALDH1A1TSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210100-A | N-/3-halo-4-/hexafluoropropoxy/-5-trifluoromethyl/phenyl and N'-difluorobenzoyl; pesticides | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0174274-B1 | PHENYLBENZOYLUREA DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-11-23 | — | — | EP | disclosed |
| EP-0174274-A1 | Phenylbenzoylurea derivatives | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |