Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489133 | 0.86 | RECQL (0.52) | RECQLRORCALDH1A1TMPRSS4TRPV1 | |
| SCHEMBL24032647 | 0.80 | RORC (0.44) | RORCALDH1A1TMPRSS4KDRTRPV1 | |
| SCHEMBL9489918 | 0.73 | MAPT (0.36) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL12144652 | 0.73 | TMPRSS4 (0.49) | RORCALDH1A1TMPRSS4KDRTRPV1 | |
| SCHEMBL9299891 | 0.72 | RECQL (0.52) | RECQLRORCALDH1A1TRPV1PDK1 | |
| SCHEMBL24032648 | 0.71 | THRB (0.43) | RORCTMPRSS4KDRTRPV1GAA | |
| SCHEMBL9640662 | 0.70 | RECQL (0.63) | RECQLRORCALDH1A1TDP1MAPT | |
| SCHEMBL12144653 | 0.69 | KDR (0.43) | RORCALDH1A1KDRTRPV1PDK1 | |
| SCHEMBL462753 | 0.69 | KDR (0.76) | ALDH1A1TMPRSS4KDRTRPV1PDK1 | |
| SCHEMBL28875490 | 0.69 | KDR (0.57) | RORCALDH1A1KDRTRPV1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210100-A | N-/3-halo-4-/hexafluoropropoxy/-5-trifluoromethyl/phenyl and N'-difluorobenzoyl; pesticides | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0174274-B1 | PHENYLBENZOYLUREA DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-11-23 | — | — | EP | disclosed |
| EP-0174274-A1 | Phenylbenzoylurea derivatives | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |