Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490735 | 0.75 | ALDH1A1 (0.38) | RECQLALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL7102659 | 0.72 | RECQL (0.43) | RECQLALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL29624830 | 0.72 | RECQL (0.43) | RECQLALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL9489128 | 0.72 | ALDH1A1 (0.37) | RECQLALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL27678042 | 0.66 | MEN1 (0.39) | HSD17B10FSCN1MEN1MAPTKMT2A | |
| SCHEMBL6441902 | 0.63 | MAPT (0.46) | ALDH1A1TSHRHSD17B10MEN1MAPT | |
| SCHEMBL9640662 | 0.62 | RECQL (0.63) | RECQLALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL7751671 | 0.61 | ALDH1A1 (0.46) | RECQLALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL4432486 | 0.60 | ALDH1A1 (0.54) | RECQLALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL7751907 | 0.59 | ALDH1A1 (0.41) | RECQLALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231152-A2 | Phenylbenzoyl ureas | CIBA-GEIGY AG (CH) | 1987-08-05 | — | — | EP | disclosed |