Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451229 | 0.83 | HTR1B (0.52) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL6271706 | 0.81 | MEN1 (0.46) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL9451333 | 0.77 | CA1 (0.55) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL9451336 | 0.77 | CYP1A2 (0.47) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL11544047 | 0.77 | LTA4H (0.46) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL9861824 | 0.76 | KMT2A (0.44) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL1345118 | 0.75 | MAOB (0.57) | DRD4DRD2DRD3NPC1HRH3 | |
| SCHEMBL9451309 | 0.74 | CA2 (0.55) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL9451338 | 0.74 | CA1 (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1332078 | 0.73 | CA12 (0.56) | KMT2AMEN1DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192785-A | Sulfamates as antiglaucoma agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-09 | — | — | US | claimed |
| US-5192785-A | Sulfamates as antiglaucoma agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-09 | — | — | US | disclosed |
| US-5025031-A | Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants | A. H. ROBINS CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |