Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490849 | 0.83 | KMT2A (0.46) | RAB9AMEN1KMT2AL3MBTL1DRD2 | |
| SCHEMBL24360927 | 0.83 | MEN1 (0.49) | HTR1BHTR1DRAB9AMAPTPKM | |
| SCHEMBL28779160 | 0.81 | RAB9A (0.49) | HTR1BHTR1DRAB9AMAPTPKM | |
| SCHEMBL7976554 | 0.79 | KCNA3 (0.52) | HTR1BHTR1DRAB9AMAPTPKM | |
| SCHEMBL1607270 | 0.79 | KCNA3 (0.56) | HTR1BHTR1DRAB9AMAPTPKM | |
| SCHEMBL12798632 | 0.76 | PKM (0.49) | HTR1BHTR1DRAB9AMAPTPKM | |
| SCHEMBL10153743 | 0.76 | HTR1B (0.53) | HTR1BHTR1DRAB9AMAPTPKM | |
| SCHEMBL18195896 | 0.76 | KCNA3 (0.40) | HTR1BHTR1DRAB9AMAPTPKM | |
| SCHEMBL1253674 | 0.76 | PKM (0.53) | RAB9AMAPTPKMKCNA3MTNR1A | |
| SCHEMBL9451235 | 0.76 | CA1 (0.58) | KCNA3TAAR1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273993-A | Antiarthritic agents; osteoporosis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |
| US-5194446-A | Antiarthritic agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-16 | — | — | US | disclosed |
| US-5025031-A | Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants | A. H. ROBINS CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |