Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 9/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206098 | 0.92 | HTR2C (0.48) | HTR2CHTR1ACYP2D6TSHRKMT2A | |
| Ocaperidone SCHEMBL29710913 | 0.80 | DRD2 (0.66) | HTR2CHTR1ACYP2D6TSHRPMP22 | |
| Ocaperidone SCHEMBL122321 | 0.80 | DRD2 (0.66) | HTR2CHTR1ACYP2D6TSHRPMP22 | |
| SCHEMBL9285766 | 0.80 | HTR1A (0.47) | HTR2CHTR1ACYP2D6TSHRKMT2A | |
| Ocaperidone SCHEMBL4590337 | 0.78 | HTR2A (0.61) | HTR2CHTR1ACYP2D6TSHRPMP22 | |
| Ocaperidone SCHEMBL4590272 | 0.78 | DRD2 (0.59) | HTR2CHTR1ACYP2D6TSHRPMP22 | |
| Ocaperidone SCHEMBL4590606 | 0.77 | HTR2A (0.59) | HTR2CHTR1ACYP2D6TSHRPMP22 | |
| SCHEMBL9491933 | 0.76 | HTR2C (0.61) | HTR2CHTR1ACYP2D6TSHRKMT2A | |
| Ocaperidone SCHEMBL4590338 | 0.76 | HTR2A (0.58) | HTR2CHTR1ACYP2D6TSHRPMP22 | |
| SCHEMBL8324484 | 0.74 | DRD2 (0.59) | HTR2CHTR1ACYP2D6TSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196425-A | Antihypertensive 3-piperidinyl-indazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-23 | — | — | US | claimed |