SCHEMBL9490952

SCHEMBL9490952

Clc1cccc(Oc2cccc(Oc3cccc(Cl)n3)c2)n1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.62
F10 P00742 5/20 0.47
F2 P00734 3/20 0.47
MAP4K4 O95819 3/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
PPARG P37231 1/20 0.42
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
ST14 Q9Y5Y6 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL959837 0.91 L3MBTL1 (0.62) L3MBTL1F10F2MAP4K4PPARG
SCHEMBL959384 0.90 L3MBTL1 (0.57) L3MBTL1F10F2MAP4K4CYP1A2
SCHEMBL9494460 0.90 L3MBTL1 (0.56) L3MBTL1F10F2MAP4K4CYP1A2
SCHEMBL2144034 0.88 L3MBTL1 (0.54) L3MBTL1F10F2MAP4K4CYP1A2
SCHEMBL17609022 0.87 L3MBTL1 (0.55) L3MBTL1F10F2MAP4K4CYP1A2
SCHEMBL9491757 0.87 L3MBTL1 (0.53) L3MBTL1F10F2MAP4K4PPARG
SCHEMBL9493641 0.86 L3MBTL1 (0.54) L3MBTL1F10F2MAP4K4CYP1A2
SCHEMBL9492874 0.85 L3MBTL1 (0.51) L3MBTL1F10F2PPARGPRSS1
SCHEMBL3457474 0.83 MAPT (0.58) L3MBTL1CYP1A2CYP2C9CYP2C19PPARG
SCHEMBL964242 0.83 L3MBTL1 (0.55) L3MBTL1F10F2MAP4K4PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255778-B1 THERMOPLASTIC AROMATIC POLYETHER-PYRIDINES AND PROCESS FOR PREPARING SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-03 EP disclosed
US-4803258-A FROM DIHALOGENOPYRIDINE AND DIOL, MOLDING MATERIALS, FILMS, WIRE COATING MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-07 US disclosed
EP-0255778-A1 Thermoplastic aromatic polyether-pyridines and process for preparing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-02-10 EP disclosed