Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490952 | 0.90 | L3MBTL1 (0.62) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 | |
| SCHEMBL9494460 | 0.85 | L3MBTL1 (0.56) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 | |
| SCHEMBL2144034 | 0.82 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 | |
| SCHEMBL17609022 | 0.82 | L3MBTL1 (0.55) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 | |
| SCHEMBL10544428 | 0.82 | CYP1A2 (0.53) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 | |
| SCHEMBL959837 | 0.82 | L3MBTL1 (0.62) | L3MBTL1MAP4K4F2F10BRAF | |
| SCHEMBL8115420 | 0.82 | MAP4K4 (0.59) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 | |
| SCHEMBL10544419 | 0.82 | CYP1A2 (0.53) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 | |
| SCHEMBL9491757 | 0.82 | L3MBTL1 (0.53) | L3MBTL1MAP4K4F2F10PPARG | |
| SCHEMBL9493641 | 0.81 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C9CYP2C19MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | L3MBTL1 4361/4885CYP1A2 1185/4885CYP2C9 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.