Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | ESRRG | P62508 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315419 | 0.92 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13577905 | 0.91 | SMN1; SMN2 (0.81) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3580293 | 0.89 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11960439 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1233587 | 0.88 | HDAC1 (0.81) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1884141 | 0.88 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5696345 | 0.85 | RAB9A (0.68) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14615882 | 0.85 | RAB9A (0.68) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13762068 | 0.85 | TMEM97 (0.67) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11960450 | 0.84 | F10 (0.62) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5191003-A | Diamide compound, improved tire gripping, vibration insulation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0470776-A1 | Rubber composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-02-12 | — | — | EP | disclosed |