Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361925 | 0.88 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8536331 | 0.86 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8359904 | 0.86 | ACHE (0.44) | AGTR1AGTR2 | |
| SCHEMBL8364591 | 0.85 | KDM4E (0.40) | AGTR1AGTR2 | |
| SCHEMBL8359346 | 0.84 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8357009 | 0.83 | TLR7 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8359916 | 0.83 | PPARG (0.39) | AGTR1AGTR2 | |
| SCHEMBL8359678 | 0.83 | PPARG (0.39) | AGTR1AGTR2 | |
| SCHEMBL8357724 | 0.83 | ACHE (0.38) | AGTR1 | |
| SCHEMBL8364565 | 0.82 | ACHE (0.37) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243054-A | Hypotensive agents, cardiovascular disorders or nervous system disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-07 | — | — | US | disclosed |