Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490984 | 0.85 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8357009 | 0.84 | TLR7 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8361925 | 0.83 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8359904 | 0.82 | ACHE (0.44) | AGTR1AGTR2 | |
| SCHEMBL8536331 | 0.82 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8357724 | 0.80 | ACHE (0.38) | AGTR1 | |
| SCHEMBL8359346 | 0.80 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8359678 | 0.79 | PPARG (0.39) | AGTR1AGTR2 | |
| SCHEMBL8359916 | 0.79 | PPARG (0.39) | AGTR1AGTR2 | |
| SCHEMBL7014979 | 0.77 | AGTR2 (0.52) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883111-A | STRONG AND LONG-LASTING ACTION BY ORAL ADMINISTRATION; HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; ALZHEIMER'S DISEASE; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5736555-A | HYPOTENSIVE AGENTS; FDA ORANGE BOOK LISTED PATENT FOR AZILSARTAN MEDOXOMIL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |