Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | NNMT | P40261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24269073 | 0.81 | — | — | |
| SCHEMBL12652755 | 0.81 | TSHR (0.36) | PNMTSLC6A2SLC6A4SLC6A3ADORA1 | |
| SCHEMBL5593560 | 0.76 | CHRM3 (0.44) | SLC6A2SLC6A4SLC6A3ADORA1 | |
| SCHEMBL24269079 | 0.72 | — | — | |
| SCHEMBL10592697 | 0.70 | POLB (0.33) | NNMT | |
| SCHEMBL21175175 | 0.67 | PNMT (0.36) | PNMT | |
| SCHEMBL4060406 | 0.66 | — | — | |
| SCHEMBL9492206 | 0.66 | — | — | |
| SCHEMBL15241808 | 0.64 | NOS1 (0.38) | PNMT | |
| SCHEMBL18102762 | 0.64 | BRD4 (0.32) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200522-A | METHOD FOR PREPARING 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1993-04-06 | — | — | US | claimed |