Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | DRD3 | P35462 | 7/20 | 0.41 |
| ▸ | FADS1 | O60427 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196697 | 0.87 | NSD2 (0.41) | GRM2NSD2DRD2DRD3FADS1 | |
| SCHEMBL9494260 | 0.80 | GRM2 (0.43) | GRM2DRD2DRD3FADS1KCNH2 | |
| SCHEMBL10434289 | 0.78 | GRM2 (0.42) | GRM2NSD2DRD2DRD3FADS1 | |
| SCHEMBL8010813 | 0.77 | ALDH1A1 (0.40) | DRD2DRD3NOTUM | |
| SCHEMBL10582421 | 0.76 | GRM2 (0.41) | GRM2NSD2DRD2DRD3FADS1 | |
| SCHEMBL10582679 | 0.76 | GRM2 (0.40) | GRM2NSD2DRD2DRD3FADS1 | |
| SCHEMBL10567430 | 0.72 | ELANE (0.40) | — | |
| SCHEMBL8240919 | 0.69 | DRD2 (0.46) | GRM2NSD2DRD2DRD3FADS1 | |
| SCHEMBL10582170 | 0.69 | FNTA (0.40) | GRM2TSHR | |
| SCHEMBL9226976 | 0.68 | GRM2 (0.35) | GRM2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266701-A | Process for production of 2-iminothiazolidines and oxazolidines | ICI AMERICAS INC. (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0349283-A1 | Novel herbicidal 2-sulfonyliminothiazolidines | ZENECA INC. (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4867782-A | BROADLEAF AND GRASSY WEEDS | ICI AMERICAS INC. (US) | 1989-09-19 | — | — | US | disclosed |