⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755850 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL4989868 | 0.69 | KEAP1 (0.36) | — | |
| SCHEMBL9204364 | 0.69 | KEAP1 (0.47) | — | |
| SCHEMBL4990874 | 0.66 | KMT2A (0.37) | — | |
| SCHEMBL8893563 | 0.65 | LOX (0.32) | — | |
| SCHEMBL17654255 | 0.65 | CNR2 (0.33) | — | |
| SCHEMBL205815 | 0.64 | — | — | |
| SCHEMBL7759568 | 0.62 | — | — | |
| SCHEMBL5220679 | 0.62 | HSP90AA1 (0.39) | — | |
| SCHEMBL3599059 | 0.61 | LOX (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | claimed |
| US-4001205-A | WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | claimed |
| CN-107690434-B | Fused tricyclic imidazopyrazine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-105829307-B | Tetrahydroimidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2020-07-24 | — | — | CN | disclosed |
| EP-3080128-B1 | IMIDAZOPYRIDAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-24 | — | — | EP | disclosed |
| EP-3080127-B1 | IMIDAZOPYRIMIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-24 | — | — | EP | disclosed |
| EP-3080123-B1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3080129-B1 | IMIDAZOTRIAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-03 | — | — | EP | disclosed |
| EP-3080130-B1 | TRIAZOLOPYRIDAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-03 | — | — | EP | disclosed |
| EP-3080112-B1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-03 | — | — | EP | disclosed |
| EP-3303337-B1 | FUSED TRICYCLIC IMIDAZO PYRAZINES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-05-27 | — | — | EP | disclosed |
| WO-2013186229-A1 | TNF -ALPHA MODULATING BENZIMIDAZOLES | UCB PHARMA S.A. (BE) | 2013-12-19 | — | — | WO | disclosed |
| EP-0203585-B1 | CUPROPHTHALOCYANINE TYPE COMPOUNDS AND DYEING METHOD USING SAID COMPOUNDS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4771132-A | CELLULOSIC FIBER DYES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0203585-A2 | Cuprophthalocyanine type compounds and dyeing method using said compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1986-12-03 | — | — | EP | disclosed |
| US-4453945-A | Process for dyeing cellulose fibers of its union fibers with reactive triazinyl dye quaternized with nicotinic acid | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0021044-B1 | PROCESS FOR DYEING CELLULOSE FIBRES AND FIBRE BLENDS CONTAINING CELLULOSE FIBRES WITH REACTIVE DYESTUFFS | BAYER AG (DE) | 1983-02-09 | — | — | EP | disclosed |
| EP-0021044-A1 | Process for dyeing cellulose fibres and fibre blends containing cellulose fibres with reactive dyestuffs | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-3933785-A | Azo compounds | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |
| US-3932366-A | FROM AMINOCARBOXYLIC ACIDS AND TRIAMINES, FIBER REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |