Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3256955 | 0.92 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL13253174 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL65794 | 0.81 | MAPT (0.61) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3025045 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3025048 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL7716054 | 0.78 | RELA (0.50) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL16983236 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL71401 | 0.77 | PTPN1 (0.73) | ALDH1A1PTPN1MAPTMEN1KMT2A | |
| SCHEMBL71402 | 0.77 | PTPN1 (0.73) | ALDH1A1PTPN1MAPTMEN1KMT2A | |
| SCHEMBL5379059 | 0.77 | PTPN1 (0.73) | ALDH1A1PTPN1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212269-A | Main chain chromophoric polymers with second order nonlinear optical properties | UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE NAVY | 1993-05-18 | — | — | US | disclosed |