Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.62 |
| ▸ | NQO2 | P16083 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491759 | 0.85 | SMN1; SMN2 (0.70) | MTNR1AKDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL17040271 | 0.85 | CES2 (0.61) | MTNR1ANQO2KDM4EMAPTCYP1A2 | |
| SCHEMBL7904484 | 0.84 | SMN1; SMN2 (0.69) | MTNR1ANQO2KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL9493169 | 0.83 | MTNR1A (0.60) | MTNR1AKDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL3719877 | 0.82 | SMN1; SMN2 (0.74) | MTNR1AKDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL9490605 | 0.82 | SMN1; SMN2 (0.55) | MTNR1AKDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL9490706 | 0.82 | SMN1; SMN2 (0.55) | MTNR1AKDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL9130202 | 0.82 | MTNR1A (0.61) | MTNR1AKDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL9496042 | 0.82 | SMN1; SMN2 (0.55) | KDM4ETP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9490321 | 0.81 | MTNR1A (0.60) | MTNR1AKDM4ETP53MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225442-A | Melatoninergic disorders | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | disclosed |