Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 8/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493503 | 1.00 | HSD11B1 (0.42) | HSD11B1RARBLIPGMEN1MAPT | |
| SCHEMBL9496996 | 0.98 | HSD11B1 (0.43) | HSD11B1RARBLIPGMEN1MAPT | |
| SCHEMBL7786742 | 0.97 | LIPG (0.44) | HSD11B1RARBLIPGMEN1MAPT | |
| SCHEMBL7781693 | 0.97 | LIPG (0.44) | HSD11B1RARBLIPGMEN1MAPT | |
| SCHEMBL7788940 | 0.95 | HSD11B1 (0.42) | HSD11B1RARBLIPGMEN1MAPT | |
| SCHEMBL17108393 | 0.91 | TYR (0.43) | HSD11B1RARBLIPGMEN1MAPT | |
| SCHEMBL9563819 | 0.89 | CYSLTR2 (0.36) | HSD11B1RARBLIPGCTSLCTSS | |
| SCHEMBL9563873 | 0.89 | CYSLTR2 (0.36) | HSD11B1RARBLIPGCTSLCTSS | |
| SCHEMBL9563920 | 0.89 | CYSLTR2 (0.36) | HSD11B1RARBLIPGCTSLCTSS | |
| SCHEMBL9563888 | 0.88 | CTSL (0.34) | HSD11B1RARBLIPGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329752-B1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0329752-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |