Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 6/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494415 | 0.78 | ADRB3 (0.53) | ADRB3ADRB2MEN1KMT2AALDH1A1 | |
| SCHEMBL9494401 | 0.78 | ADRB3 (0.53) | ADRB3ADRB2MEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL9787778 | 0.75 | ADRB3 (0.55) | ADRB3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9492908 | 0.75 | ADRB3 (0.42) | ADRB3ADRB2ADRB1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9787821 | 0.72 | ADRB3 (0.45) | ADRB3ADRB2ADRB1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9787761 | 0.71 | ADRB3 (0.45) | ADRB3ADRB2ADRB1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9787715 | 0.71 | ADRB3 (0.49) | ADRB3ADRB1MEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL9787807 | 0.70 | ADRB3 (0.54) | ADRB3ADRB1MEN1KMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL9787785 | 0.70 | ADRB3 (0.47) | ADRB3ADRB2ADRB1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9787744 | 0.68 | KDM4E (0.48) | ADRB3ADRB1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345591-B1 | PROPANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-31 | — | — | EP | claimed |