Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9787761 | 0.95 | ADRB3 (0.45) | ADRB3ADRB1LMNAHTTADRB2 | |
| SCHEMBL9494401 | 0.83 | ADRB3 (0.53) | ADRB3ADRB2MEN1ALDH1A1KMT2A | |
| SCHEMBL9494415 | 0.83 | ADRB3 (0.53) | ADRB3ADRB2MEN1ALDH1A1KMT2A | |
| Oxalic Acid SCHEMBL9787778 | 0.79 | ADRB3 (0.55) | ADRB3LMNAMEN1ALDH1A1KMT2A | |
| Oxalic Acid SCHEMBL9787821 | 0.78 | ADRB3 (0.45) | ADRB3ADRB1LMNAADRB2MEN1 | |
| Oxalic Acid SCHEMBL9787715 | 0.75 | ADRB3 (0.49) | ADRB3ADRB1LMNAMEN1ALDH1A1 | |
| SCHEMBL9492909 | 0.75 | ADRB3 (0.38) | ADRB3ADRB1LMNAHTTADRB2 | |
| SCHEMBL9787748 | 0.75 | LMNA (0.43) | LMNAHTTMEN1ALDH1A1KMT2A | |
| Oxalic Acid SCHEMBL9787807 | 0.75 | ADRB3 (0.54) | ADRB3ADRB1MEN1KMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL9787785 | 0.74 | ADRB3 (0.47) | ADRB3ADRB1ADRB2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345591-B1 | PROPANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |