Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660328 | 0.83 | ERN1 (0.48) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL1067996 | 0.83 | ERN1 (0.52) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL6060504 | 0.83 | ERN1 (0.42) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL30417210 | 0.83 | ERN1 (0.52) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL2429712 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL320379 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL209239 | 0.78 | HSD17B10 (0.50) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL6111862 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL17056841 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AERN1 | |
| SCHEMBL6061080 | 0.78 | ERN1 (0.38) | ALDH1A1TDP1MEN1KMT2AERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459422-A | Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118459420-A | Thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| CN-108103540-B | Tin alloy electroplating solution | 永星化工(上海)有限公司 | 2020-01-07 | — | — | CN | claimed |
| EP-2595948-B1 | A METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO LABORATORIES LTD (IE) | 2019-09-04 | — | — | EP | claimed |
| EP-3106477-B1 | (METH)ACRYLIC ACID ESTER COMPOUND AND PRODUCTION METHOD THEREFOR | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-08-29 | — | — | EP | claimed |
| CN-108103540-A | Tin alloy electric plating liquid | 永星化工(上海)有限公司 | 2018-06-01 | — | — | CN | claimed |
| CN-106414480-A | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | 莫纳什大学 | 2017-02-15 | — | — | CN | claimed |
| EP-3126376-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | Monash University (AU) | 2017-02-08 | — | — | EP | claimed |
| WO-2004018451-A1 | PYRIDAZINONE-DERIVATIVES AS PDE4 INHIBITORS | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | claimed |
| EP-1390336-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2004-02-25 | — | — | EP | claimed |
| US-20030162963-A1 | Novel expanded porphyrins and process for the synthesis thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2003-08-28 | — | — | US | claimed |
| EP-1306380-A1 | NOVEL EXPANDED PORPHYRINS AND PROCESS FOR THE SYNTHESIS THEREOF | Japan Science and Technology Corporation (JP) | 2003-05-02 | — | — | EP | claimed |
| EP-1216251-B1 | REGIOSELECTIVE SYNTHESIS OF RAPAMYCIN DERIVATIVES | WYETH CORP (US) | 2003-02-26 | — | — | EP | claimed |
| WO-2002096849-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-12-05 | — | — | WO | claimed |
| EP-1216251-A2 | REGIOSELECTIVE SYNTHESIS OF RAPAMYCIN DERIVATIVES | Wyeth (US) | 2002-06-26 | — | — | EP | claimed |
| US-20010039338-A1 | Regioselective synthesis of rapamycin derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-08 | — | — | US | claimed |
| WO-2001023395-A2 | REGIOSELECTIVE SYNTHESIS OF RAPAMYCIN DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-04-05 | — | — | WO | claimed |
| US-4727079-A | Brain-specific dopaminergic activity involving dihydropyridine carboxamides, dihydroquinoline and isoquinoline carboxamides | UNIVERSITY OF FLORIDA (US) | 1988-02-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162963-A1 | Novel expanded porphyrins and process for the synthesis thereof | AAAS, PAM, AHR | ALDH1A1 3008/4885TDP1 4734/4885MEN1 952/4885 |
| US-20010039338-A1 | Regioselective synthesis of rapamycin derivatives | RICTOR, MTOR, RPTOR | ALDH1A1 4478/4885TDP1 4808/4885MEN1 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.