Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492999 | 1.00 | PSMB5 (0.51) | PSMB5ALDH1A1ACEPOLBCHRNB2 | |
| SCHEMBL9492365 | 0.93 | FAAH (0.55) | PSMB5ALDH1A1ACEPOLBFAAH | |
| SCHEMBL9492370 | 0.93 | FAAH (0.55) | PSMB5ALDH1A1ACEPOLBFAAH | |
| SCHEMBL9493900 | 0.92 | FAAH (0.59) | PSMB5FAAHHDAC1HDAC6 | |
| SCHEMBL9493898 | 0.92 | FAAH (0.59) | PSMB5FAAHHDAC1HDAC6 | |
| SCHEMBL9493061 | 0.90 | ALDH1A1 (0.51) | PSMB5ALDH1A1ACEPOLBTACR1 | |
| SCHEMBL9493066 | 0.90 | ALDH1A1 (0.51) | PSMB5ALDH1A1ACEPOLBTACR1 | |
| SCHEMBL9488665 | 0.85 | TP53 (0.59) | PSMB5ALDH1A1ACEPOLBCHRNB2 | |
| SCHEMBL9488674 | 0.85 | TP53 (0.59) | PSMB5ALDH1A1ACEPOLBCHRNB2 | |
| SCHEMBL9492544 | 0.85 | ALDH1A1 (0.51) | ALDH1A1ACEPOLBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |