Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18898419 | 0.88 | TSHR (0.45) | LMNAHRH1SLC6A3CHRM2CHRM1 | |
| SCHEMBL8860874 | 0.82 | RIPK1 (0.44) | LMNARIPK1HRH1SLC6A3CACNA1F | |
| SCHEMBL8608404 | 0.79 | RIPK1 (0.41) | LMNARIPK1HRH1SLC6A3CACNA1F | |
| SCHEMBL68538 | 0.79 | RIPK1 (0.45) | LMNARIPK1HRH1SLC6A3CACNA1F | |
| SCHEMBL4329684 | 0.79 | RIPK1 (0.41) | LMNARIPK1HRH1SLC6A3CACNA1F | |
| SCHEMBL8634300 | 0.79 | RIPK1 (0.44) | LMNARIPK1HRH1SLC6A3CACNA1F | |
| SCHEMBL23394679 | 0.79 | RIPK1 (0.33) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL27450995 | 0.79 | RIPK1 (0.41) | LMNARIPK1HTR2A | |
| SCHEMBL9817040 | 0.78 | LMNA (0.44) | LMNARIPK1HRH1TAAR1HTR2A | |
| SCHEMBL1823949 | 0.77 | TRPA1 (0.55) | LMNARIPK1HRH1SLC6A3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180799-A | Organolithium-Organoaluminum Catalyst | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-19 | — | — | US | disclosed |
| EP-0434316-A1 | Processes | ZENECA LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |