SCHEMBL1056798

SCHEMBL1056798

CCN(CC)c1ccc(C=NN(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.74
KMT2A Q03164 7/20 0.74
MEN1 O00255 6/20 0.74
MCL1 Q07820 2/20 0.74
SMN1; SMN2 Q16637 1/20 0.74
MAPT P10636 12/20 0.68
GAA P10253 4/20 0.68
HSP90AA1 P07900 1/20 0.68
LMNA P02545 7/20 0.56
MAPK1 P28482 6/20 0.56
POLB P06746 2/20 0.56
PKM P14618 1/20 0.56
KDM4E B2RXH2 8/20 0.55
HPGD P15428 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
MITF O75030 1/20 0.55
RAD52 P43351 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
ATM Q13315 1/20 0.55
TSHR P16473 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702643 1.00 ALDH1A1 (0.74) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL14337651 0.96 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL130652 0.88 ALDH1A1 (0.78) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL10145000 0.87 ALDH1A1 (0.77) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL9809673 0.85 MAPT (0.79) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL9809671 0.85 MAPT (0.79) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL11266387 0.84 G6PC1 (0.58) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL9493442 0.83 TSHR (0.63) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL11238432 0.81 MAPT (1.00) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL11238435 0.81 MAPT (1.00) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP claimed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US claimed
US-20150185627-A1 Method of Producing Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-20150185629-A1 Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-8374532-B2 Image forming apparatus RICOH COMPANY, LIMITED (JP) 2013-02-12 US disclosed
US-8178265-B2 Electrophotographic photoreceptor having a spectral marker and electrophotographic printer using the same LEXMARK INTERNATIONAL, INC. (US) 2012-05-15 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-7955769-B2 Control of crazing, cracking or crystallization of a charge transport layer in a photoconductor LEXMARK INTERNATIONAL, INC. (US) 2011-06-07 US disclosed
US-20110008069-A1 IMAGE FORMING APPARATUS RICOH COMPANY LIMITED (JP) 2011-01-13 US disclosed
US-4933244-A Phenolic epoxy polymer or polyester and charge transporting small molecule at interface between a charge generator layer and a charge transport layer XEROX CORPORATION (US) 1990-06-12 US disclosed
US-4931349-A Electrophotographic photoreceptor having an azo compound DAINICHISEIKA COLOR & CHEMICALS MFG. CO. (JP) 1990-06-05 US disclosed
US-4921773-A Process for preparing an electrophotographic imaging member XEROX CORPORATION (US) 1990-05-01 US disclosed
US-4895783-A SOLVENT RESISTANCE, WEAR RESISTANCE XEROX CORPORATION (US) 1990-01-23 US disclosed
EP-0322823-A2 Electrophotographic photoreceptor DAINICHI SEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1989-07-05 EP disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4423129-A CHARGE TRANSFER COMPOUND CANON KABUSHIKI KAISHA (JP) 1983-12-27 US disclosed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US disclosed