SCHEMBL14337651

SCHEMBL14337651

CCN(Cc1ccccc1)c1ccc(C=NN(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.72
KMT2A Q03164 7/20 0.72
MEN1 O00255 6/20 0.72
MCL1 Q07820 2/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
MAPT P10636 12/20 0.66
GAA P10253 4/20 0.66
HSP90AA1 P07900 1/20 0.66
TSHR P16473 1/20 0.61
KDM4E B2RXH2 8/20 0.61
LMNA P02545 7/20 0.61
MAPK1 P28482 6/20 0.61
HPGD P15428 4/20 0.61
TDP1 Q9NUW8 3/20 0.61
MITF O75030 1/20 0.61
RAD52 P43351 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 2/20 0.54
PKM P14618 1/20 0.54
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702643 0.96 ALDH1A1 (0.74) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL1056798 0.96 ALDH1A1 (0.74) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL9493442 0.87 TSHR (0.63) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL130652 0.87 ALDH1A1 (0.78) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL10145000 0.86 ALDH1A1 (0.77) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL5858647 0.84 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL5858649 0.84 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL9809673 0.83 MAPT (0.79) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL9809671 0.83 MAPT (0.79) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2
SCHEMBL11266387 0.80 G6PC1 (0.58) ALDH1A1KMT2AMEN1MCL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309557-B2 Image forming apparatus and image forming method KONICA MINOLTA HOLDINGS, INC. (JP) 2007-12-18 US disclosed
US-7309557-B2 Image forming apparatus and image forming method KONICA MINOLTA HOLDINGS, INC. (JP) 2007-12-18 US disclosed