Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.51 |
| ▸ | EDNRB | P24530 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045052 | 0.92 | MEN1 (0.55) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9043805 | 0.91 | EDNRA (0.49) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9045446 | 0.89 | KIT (0.48) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9053125 | 0.89 | EDNRA (0.47) | EDNRAEDNRBKMT2AMAPTUCHL1 | |
| SCHEMBL9046709 | 0.88 | ALDH1A1 (0.60) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9045149 | 0.86 | NPSR1 (0.51) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9046700 | 0.85 | EDNRA (0.49) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9493462 | 0.84 | EDNRB (0.44) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9047567 | 0.84 | EDNRA (0.51) | EDNRAEDNRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6785011 | 0.84 | EDNRA (0.67) | EDNRAEDNRBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270313-A | Treatment of circulatory disorders | HOFFMANN-LA ROCHE INC. (US) | 1993-12-14 | — | — | US | disclosed |