Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898281 | 0.88 | LMNA (0.67) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL28824947 | 0.88 | LMNA (0.67) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL2712558 | 0.88 | LMNA (0.67) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL16616153 | 0.86 | MEN1 (0.62) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL29898323 | 0.84 | RAB9A (0.76) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL28824933 | 0.84 | RAB9A (0.76) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL5255345 | 0.83 | LMNA (0.71) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL29898266 | 0.81 | RAB9A (0.78) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL28824958 | 0.81 | RAB9A (0.78) | RAB9AMAPTSMN1; SMN2NPC1AHR | |
| SCHEMBL10378109 | 0.80 | HTT (0.54) | RAB9AMAPTSMN1; SMN2NPC1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |