Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495470 | 0.88 | RAB9A (0.40) | CISD2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9497849 | 0.79 | — | — | |
| SCHEMBL5252939 | 0.72 | RAB9A (0.45) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9494438 | 0.70 | EPHX1 (0.40) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9496918 | 0.70 | KMT2A (0.42) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9494086 | 0.69 | CISD2 (0.39) | CISD2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9499230 | 0.69 | TSHR (0.39) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29576788 | 0.68 | MAPT (0.35) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9495137 | 0.67 | — | — | |
| SCHEMBL9497044 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |